Profile
Apeksha Singh
Apeksha started the Biomath Ph.D. Program at UCLA in September 2020 under the supervision of Professor Alexander Hoffmann, after completing two years of medical school as a part of the UCLA-Caltech Medical Scientist Training Program. Before starting at UCLA, Apeksha completed her Bachelor’s degree in Applied Mathematics and Molecular and Cell Biology at UC Berkeley. During her undergraduate career, she was fortunate to be exposed to research in Computational Biology, which motivated her interest to pursue a PhD.
She joined Dr. Hoffmann’s lab because she was interested in working more closely with experimental data and applying mathematical models to better understand biological mechanisms. Apeksha studied how inflammation and aging alter the differentiation and proliferation of cells in early hematopoiesis, promoting myeloid bias. She used different population dynamics models to interpret changes in cell abundance captured by flow cytometry and single-cell RNA sequencing experiments in both mouse models and human patients. Having completed her graduate studies, Apeksha is currently returning to medical school to complete her MD. She plans to pursue both clinical and research work in her future career.