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Single-cell sequencing is transforming our understanding of complex tissues but their application to large population cohorts has been limited. Large sample sizes are particularly important for studying complex autoimmune diseases such as lupus where patients present a variety of symptoms and may respond very differently to current treatments.
Professor Valerie Arboleda was inducted into the American Society for Clinical Investigation (ASCI) on April 8, 2022 during the AAP/ASCI/APSA Joint Meeting in Chicago.
Single-cell RNA sequencing (scRNA-seq) technologies have revolutionized biomedical sciences by enabling genome-wide profiling of gene expression levels at an unprecedented single-cell resolution. A distinct characteristic of scRNA-seq data is the vast proportion of zeros unseen in bulk RNA-seq data.